nCounter® MAX Analysis System

Digital Molecular Barcoding Technology for Translational Research

The nCounter® MAX Analysis System is Fully automated and easy-to-use system which provides everything you need to complete cost-effectively in your projects in record time. This technology is more accurate and highly multiplexed than qPCR and simpler than NGS, the nCounter® MAX allows for digital examination of multiple pathways in a single tube in an extraction-free workflow requiring only 15 minutes of hands on time. Accelerate your research by spending less time on sample prep and perform your own data analysis using the included nSolver Analysis Software.

The nCounter® Max platform is a complete solution for digitally detecting and counting large sets of molecules and provides tools for researchers solving problems in the areas of translational research and molecular diagnostics. This Platform is specifically designed for core labs and possess expandable throughput to analyze differential expression of genes and proteins.

Hands-on Time

  • Prepare hybridized samples: 5 minutes
  • Initiate run on Prep Station: 5 minutes
  • Transfer to Digital Analyzer: 5 minutes

Run Time

  • Prep Station: 2.5 to 3 hours
  • Digital Analyzer: 0.5 to 5 hours

Runs per Day

  • Prep Station: 4 runs
  • Digital Analyzer: capacity for 6 cartridges

nCounter Cartridge Format

  • Prep Station purifies hybridized samples and deposits them onto a glass slide which is transferred to the Digital Analyzer.

NanoString’s nCounter technology is molecular barcoding technology which digitally detects individual target molecules through the use of a unique probe pair for each target of interest. The probe pair consists of a color-coded Reporter probe, which carries the visible signal on its 5’ end, and a Capture probe, which carries a biotin moiety on the 3’ end. with a specific target. Each Reporter probe has six positions, and each position can be one of four colors. A large diversity of probes can be mixed together with the sample in a single well, with each Reporter probe interacting with a specific target. These target-probe complexes are then individually resolved and identified during data collection.

  • Operating temperature: 18–28°C
  • Humidity: 30-80% (non-condensing)
  • Pollution degree: 2
  • Power source: 100–240 VAC, 50–60 Hz
  • Power draw: 610 VA
  • Dimensions (Prep Station): 67 x 89 x 63 cm
  • Dimensions (Digital Analyzer): 66 x 66 x 48 cm
  • Weight (Prep Station): 120 kg
  • Weight (Digital Analyzer): 67 kg
  • Gene Expression Analysis - Analyze the expression levels of up to 800 genes simultaneously.
  • miRNA Expression - Profile miRBase high confidence and published clinical miRNAs. Multiplexed target profiling of miRNA transcriptomes in a single reaction.
  • miRGE Expression Analysis - Simultaneously profile miRNA and mRNA expression in a single reaction, Profile FFPE samples as well as other difficult sample types.
  • Copy Number Variation Analysis - Profile up to 800 regions of the human genome in a single reaction, Better, faster results with less effort than PCR or arrays.
  • lncRNA Expression Analysis - High precision, digital quantification of lncRNAs, Analyze up to 800 lncRNAs in a single reaction with no amplification.
  • Leukemia Fusion Gene Analysis - Profile a comprehensive set of fusion genes in different leukemia subtypes.
  • Single Cell Analysis - Obtain single cell sensitivity with reverse transcription and limited amplification.
  • ChIP-String Assays - Skip the hassle of library prep and amplification when analyzing ChIP'd material.
  • RNA:Protein Profiling - Measure RNA and protein simultaneously for true multi-omic data.
  • nSolver™ Analysis Software (nSolver™ 3.0)
  • nCounter® Advanced Analysis Software

nCounter System Quick Tour
nCounter Analysis System - Direct Digital Counting of Nucleic Acids
Single Cell Gene Expression Analysis with the nCounter® System
FFPE Simplified: The nCounter® Analysis System and FFPE Samples
Cancer Research and the nCounter® Analysis System: Digital Profiling Technology for Cancer Biology
Video nSolver Analysis
nCounter Prep Station
nCounter Digital Analyzer
Introduction and QC results