Cell Signaling and Technology (CST)

Cell Signaling Technology (CST) is a private, family-owned company, founded by scientists and dedicated to providing the world’s highest quality, innovative research and diagnostic products to accelerate biological understanding and enable personalized medicine. Our employees operate worldwide from our U.S. headquarters in Massachusetts, and our offices in the Netherlands, China, and Japan.

CST Product Range

Primary Antibodies

Our primary antibodies have been tested and validated on the lot level by our in-house team of scientists for specificity, sensitivity, and reproducibility.

Antibody Samplers

Antibody Sampler Kits contain sample sizes of several antibodies directed against a protein, pathway or cellular process of interest, as well as secondary antibodies.

Secondary Antibodies

Secondary Antibodies for varied applications such as western blot, immunohistochemistry, immunocytochemistry, flow cytometry.

Antibody Conjugates

CST provides direct conjugated primary antibodies and custom conjugation services


Wide selection of sandwich antibody assays measuring important cellular signaling nodes and other cellular target proteins .

ChIP Kits & Reagents

These high quality antibodies provide better lot-to-lot consistency and target specificity making them the ideal choice for your ChIP-seq experiments.

Proteomic Analysis Products

Self developed PTMScan® technology which allows identification and quantification of hundreds to thousands of even the lowest abundance peptides, and provides a more focused approach to peptide enrichment than other strategies

Cellular Assay Kits

CST provides cellular assay kits covering a wide range of research areas including Apoptosis, Cell Cycle, Signal Transduction and Metabolism

WB & IP Reagents

From sample preparation to detection, everything you need for a more efficient and economical western blot is now found in one easy kit.


SignalSilence® siRNA are potent double-stranded RNA molecules that selectively inhibit protein expression in a cell. At CST, two equally potent siRNAs are available for each target (siRNA I and II)

Activators & Inhibitors

Chemical modulators which are useful in the interrogation of key signaling nodes and pathways in combination with our activation state and total protein antibodies.

Experimental Controls

Isotype control antibodies are used to estimate non-specific binding of primary antibodies due to Fc receptor binding or other protein-protein interactions.

Buffers & Dyes

Wide range of Buffers and dyes that are used in various applications like WB, IF , F , IHC